Research Articles
Low-cost microfluidic electrochemical paper-based device to detect glucose
Authors:
W. T. H. Fernando,
University of Colombo, Colombo, LK
About W. T. H.
Department of Chemistry
H. K. V. S. Jayarathna,
University of Colombo, Colombo, LK
About H. K. V. S.
Department of Chemistry
M. N. Kaumal
University of Colombo, Colombo, LK
About M. N.
Department of Chemistry
Abstract
Continuous monitoring of the level of glucose is essential to maintain the health of a diabetic patient. The use of invasive methods to obtain blood samples to detect glucose is the current method, but such methods may not be preferred by patients. Non-invasive methods such as the determination of glucose based on saliva or sweat can be preferred by patients for continuous monitoring. A low-cost electrochemical microfluidic paper-based analytical device (µPAD) suitable to monitor glucose levels using sweat and saliva is introduced. This device is extremely low-cost due to the use of a paper matrix and varnish for the fabrication of paper. Pseudo-reference stainless steel is used with a working electrode anodized using sodium potassium tartrate tetrahydrate for the development of a three-electrode system. Cyclic voltammetric-based analysis of glucose with µPAD produced a linear response in the working range of 1-10 mmol dm-3 with a limit of detection of 0.058 mol dm-3. The detection of diabetic conditions using saliva and sweat is possible using the device by correlating to the blood glucose levels using prior literature data.
How to Cite:
Fernando, W.T.H., Jayarathna, H.K.V.S. and Kaumal, M.N., 2022. Low-cost microfluidic electrochemical paper-based device to detect glucose. Journal of Science of the University of Kelaniya Sri Lanka, 15(1), pp.21–33. DOI: http://doi.org/10.4038/josuk.v15i1.8043
Published on
05 Apr 2022.
Peer Reviewed
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